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THC VS THC-V

Posted by Clint Hash on Mar 10th 2022

THC VS THC-V

What Is the Cannabinoid THCV, and why you Should Try It?

You, like many others, are probably wondering what THCV is right now. The little-known cannabinoid, on the other hand, has a plethora of potential benefits.

But, if that's the case, why haven't we heard anything about it before? Right?

Unfortunately, because THCV is considered a minor cannabinoid (meaning it's normally present in low concentrations in the Cannabis sativa plant) and is difficult to utilize in big quantities, it's only been identified in products like CBD oils alongside other cannabinoids. However, as CBD and a couple of the other hundred or so cannabinoids gain popularity, more attention is being directed to those little-known hitchhikers.

Since we've already addressed CBG (cannabigerol) and CBN (cannabinol) in previous articles, it's only fair that we move on to a couple of the lesser-known cannabinoids that we include in our broad spectrum CBD formula and/or full spectrum products. As a result, you're undoubtedly left with a lot of questions, such as:

What exactly is THCV?

What exactly does it do?

Is THCV synonymous with THC?

Is THCV legal in the United States?

Is there any risk of THCV adverse effects?

Does it give you a high?

THCV is a kind of cannabinoid.

What effect does THCV have on your endocannabinoid system?

What exactly is THCV?

Tetrahydrocannabivarin, or THCV, is one of more than a hundred cannabinoids present in the Cannabis sativa plant. Yes, THCV, like CBG and CBN, is the most recent cannabinoid to enter the spotlight. So, what precisely makes this cannabinoid so unique?

For one thing, THCV, like CBG, has a very similar molecular structure to THC (just as the name suggests). THCV, like CBG, can interact with both your CB1 and CB2 receptors, as we'll see later. While THCV has several potential health benefits, many research attempting to address the question "what is THCV?" are still in their early stages. Having said that, mouse studies have yielded some encouraging findings.

Because it is present in lesser amounts than the other major cannabinoids, such as THC and CBD, THCV is classified as a minor cannabinoid. While genetics play a role in determining the ratio of cannabinoids in a specific strain of Cannabis sativa, the best way to find out if a product contains THCV is to look at the label and cross-reference it with the company's ISO-certified third-party lab test results, or Certificate of Analysis.

What Is the Function of THCV?

Several studies have revealed that, despite its similarities to THC, THCV interacts with your body surprisingly differently. Rather of giving you the munchies, it may actually reduce your appetite and cause you to lose weight. And, rather than calming you down, it is frequently said to provide users with a burst of energy. However, it is vital to note that the above-mentioned research were only conducted on rats, and human trials have not yet taken place.

Nonetheless, THCV appears to have in common with the majority of other cannabinoids in that it is used to relax and relieve tension.

None of the research employing THCV have revealed any significant negative effects. However, if you go seeking for a THCV extract or Cannabis sativa goods high in THCV, you will most likely be disappointed because they are not widely available, and the few that do exist are rather pricey.


THCV vs. THC: Is THCV Addicting?

While THCV has a similar chemical structure to THC (without a longer hydrocarbon chain) and thus some psychotropic effects, you would need to drink an extraordinarily large amount of THCV to become high. This implies that, while it is present in the majority of conventional CBD products, the THCV amount is considerably too low to cause intoxication.

In addition, THCV differs from THC in how it interacts with CB1 receptors. While THC stimulates your hunger by activating the CB1 receptor, THCV actually suppresses it (leading to appetite suppression).

THC is well recognized for using the CB1 receptor to produce a psychoactive reaction known as a "high," but preliminary research suggests that THCV may actually negate THC's psychoactive characteristics.

Is THCV legal in the United States?

Yes, according to the 2018 Farm Bill, THCV is no longer a federally illegal substance as long as it is derived from industrial hemp rather than marijuana.

In fact, both our broad spectrum CBD and full spectrum CBD products include trace amounts of THCV. There isn't enough of it in our present products to produce the kinds of outcomes shown in studies (so don't use our products as weight loss pills or anything), but its presence promotes the entourage effect, which adds to overall wellness.



What Exactly Are Cannabinoids?

A cannabinoid is a chemical molecule that binds to or interacts with the cannabinoid receptors in your endocannabinoid system. Regardless of country of origin. Yes, cannabinoids are not just found in the Cannabis sativa plant, but they can also be produced by your own body. The distinction is that the cannabinoids produced by your body are known as endocannabinoids (hence the name of the endocannabinoid system).

Exogenous cannabinoids, or phytocannabinoids, are those created outside of your body, such as cannabinoids obtained from the Cannabis sativa plant. Exogenous is defined as something that grew or originated outside of an organism. That organism, in this scenario, is you.

All of this is to suggest that your internal endocannabinoid system works on a regular basis whether or not you take CBD, THC, THCV, or any other exogenous cannabinoid. Cannabinoids are not harmful or dangerous in and of themselves; they simply impact how your body functions and are mostly responsible for assisting you in maintaining homeostasis as part of a negative feedback loop.

Consider homeostasis to be a balance scale: when an internal or external influence is applied to one side, your body responds by producing the endocannabinoids required to bring the two scales back into balance. Only when one side of the scale shifts will your body respond in order to balance it out. Exogenous cannabinoids can then be used to supplement your natural endocannabinoids by utilizing your body's inherent endocannabinoid system.

CBD, THC, CBN, and CBG are some of the most prominent phytocannabinoids utilized to help strengthen your endocannabinoid system. CBD (cannabidiol) and THC (tetrahydrocannabinol) are the cannabinoids that receive the most attention, but that is swiftly changing as more research on CBN (cannabinol) and CBG (cannabigerol) is being undertaken. Only time will tell if THCV will become one of the top five most well-known cannabinoids.


Endocannabinoid System

The endocannabinoid system (ECS) is a sophisticated network that enables higher-level communication between your brain and body. Your ECS monitors and regulates everything from your mood and energy level to your sleep patterns and immune system. It is made up of endocannabinoids, enzymes, and cannabinoid receptors. The ECS is a part of both your central nervous system (CNS) and your peripheral nervous system (PNS), and it helps your body function on a daily basis.

But the ECS does more than just help us maintain homeostasis and function normally: it also plays an important part in our species' survival by informing us when to sleep or eat, experiencing the appropriate emotions at the right moment, and even regulating your body temperature. Some scientists have even suggested that low levels of endocannabinoids can lead to clinical endocannabinoid deficiency (CECD), also known as ECS dysfunction, a condition in which your health begins to decline.

The endocannabinoid system is a very busy physiological apparatus that operates at all hours of the day and night as necessary, whether by using your body's endogenous cannabinoids or those found in the Cannabis sativa plant, such as CBD and THCV.


CB1 and CB2 Receptors

We've already addressed CB1 and CB2 receptors several times, so here's a refresher on how they work within your endocannabinoid system and what their principal functions are. Cannabinoid receptors are found all over your body and are classified into two types: CB1 receptors, which are virtually entirely active through your central nervous system, and CB2 receptors, which are mostly found in your peripheral nervous system.

Cannabinoids can then bind to either CB1 or CB2 receptors, or both. A given cannabinoid can have varied effects depending on the type of cannabinoid receptor and the location of that receptor in your body.

Cannabinoid receptors function within your body by influencing your mood, hunger, immune system, memory retention, muscles, skin, respiratory system, and so much more via your CNS (containing the brain and spinal cord) and PNS (composed of nerve fibers and immune cells). And their primary function is to communicate information amongst your cells about potential changes in your health and wellness, also known as homeostasis.

So, when it comes to questions like "What exactly is THCV?" as well as "How will a specific cannabinoid impact me?" A big part of the solution lies in determining which cannabinoid receptor(s) they bind to, block, or interact with in general.

In fact, one of the primary reasons why THCV can lower hunger is due to its interaction with CB1 receptors. Or, more precisely, its ability to obstruct said receptor. THCV is hypothesized to reduce the body's natural appetite signals by blocking CB1 receptors, which are significantly involved in triggering the body's appetite response.

Unfortunately, despite everything we know so far about the endocannabinoid system, cannabinoids, and cannabinoid receptors, there is still a lot more to understand about the roles these systems play in our bodies. So much so that we've only scratched the surface of what our endocannabinoid systems are capable of.



Endocannabinoids, also known as Naturally Occurring Cannabinoids

Remember how we said that your body creates cannabinoids on a regular basis? Because your body only generates endocannabinoids as needed, and they have an extremely short half life, establishing a baseline for a person's average endocannabinoid levels might be challenging.

While endocannabinoids are created naturally throughout your body, they do not become active in your endocannabinoid system unless they interact with a cannabinoid receptor. That being said, we do know that anandamide (AEA) and 2-arachidonoylglycerol are the two main endocannabinoids, or endogenous cannabinoids, that keep your body working (2-AG). Both have a unique and important link with your CB1 and CB2 receptors.

Anandamide is known as the "bliss molecule" because it regulates your mood and interacts with your cannabinoid receptors in the same way as THC does. Anandamide is produced by your body on an as-needed basis to aid in mood modulation, binding to both CB1 and CB2 receptors. Anandamide, on the other hand, has a greater affinity for CB1 receptors. It is also easily dismantled once it has served its purpose.

A 2015 study on mice and humans discovered that increased anandamide concentrations may not only improve your mood but also assist manage your fear response. Anandamide levels were found to increase after exercise in a 2020 study, lending credibility to the hypothesis that exercise can genuinely boost your mood.

2-Arachidonoylglycerol, on the other hand, is the major CB2 receptor binding molecule and the most abundant endocannabinoid in your body. The primary functions of 2-AG include pain control, hunger regulation, immune system management, and circulatory and cardiovascular system regulation.

To Conclude

Keep an eye on our often updated blog for further information on how cannabis work within your endocannabinoid system or for answers to questions like "What is THCV?" There are more coming to us now. We have to explain THCP, HHC, HHC-O, and many more to come from what I hear.

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